I-Trifmeyopyrim sisicelo se-PCT sifakwe kwi-DUPON kwi-DEATED States ngoDisemba 22, 2011. Ifumene ugunyaziso lwepatent eTshayina, i-United States kunye namanye amazwe kunye namanye amazwe kunye ne-rab55.
Indlela yokwenziwa
Zimbini iindlela eziphambili zokwenziwa ze-trifmeyopyrim, zombini kunye ne-N- (i-5-pyrimidaminel) ye-methyl-2-pyrinamine kunye ne-2- (i-2- (i-tyifluoromethyl) i-phenyl] Maloni eziPhakathi.
Kwindlela yoku-1, n- (i-5-pyrimidiny) i-methyl-2-Pyrinamine ilungiselelwe ngokusebenzisa i-2-i-Aminopyrine njengezinto ezi-5 zokuqalisa kunye nokuncitshiswa kwe-sodium borohydride, kwaye amanyathelo anengqondo. I-m-trifluoromethyl icofene kunye ne-dimthyl masbue kunye ne-dimyeyl zidityanisiwe ukufumana i-dimthyl 2- [3- (i-trifluoromethyl) phenyl] I-Phenyl] I-Phenyl Sconakar] Malonid. Esi siPhakathi sisetyenziselwa ukulungiselela i-trifduoropyrimine ngentshayelelo kunye nokususwa okukhulu kweqela eliphuma kwiqela leTrivlorophenol.
Ukulungiswa kwe-N- (5-pyrimidinyl) I-methyl-2-pyrinamine kunye ne-dimtherinamine kunye ne-dimtheridamine kunye ne-3- (i-trifluoromethy) i-phenyl] i-scheme ye-2. Umahluko yile dimyethyl 2- [3- (trifluoromethyl) phenyl] Maloni of Shydrolysis Imveliso ye-2- [3-
Ithemba lesicelo
I-Trifmeyopyrim luhlobo olutsha lwe-pyrimidine ye-pyrimidine kwaye luhlobo olutsha lwesinambuzane. Isebenza kwi-Acetycholic Acetylline I-trifluopyrimidine ibophelelene ngokukhuphisana ngokhuphiswano kwi-orthoterc kwi-Nachr, ethintela le ndawo yokubopha. Ukucutha iimpembelelo ze-nerve yezinambuzane okanye ibhloko ye-verve, kwaye ekugqibeleni ichaphazele indlela yokuziphatha yomzimba enjengokutya kunye nokuzala, okukhokelela ekufeni.
I-Trifmeyopyrim ine-anses elungileyo yenkqubo, ixhathise i-ersion yemvula, kwaye inefuthe elide ngakumbi kunemveliso efanayo. Iziphumo zovavanyo zibonisa ukuba i-compound isebenza kakhulu, inefuthe lokulawula kakuhle kwi-lePidoptera naseHomoptera, kwaye ineempawu zokusebenza kakuhle, ukhuseleko kunye nobuhlobo bokusingqongileyo. I-trifluoropyrimidine inokukhuthaza ukukhula kwerayisi kwaye inefuthe elihle lokuphucula umgangatho kunye nesivuno. Izityalo ezibhalisiweyo zeli chiza ikakhulu yirayisi, kwaye isitshizi seFoliaar sisetyenziselwa ukulawula ii-rodicers kunye namagqabi.
Njengomntu wokuqala wentengiso we-reecidinine inishtifide, i-trifmeyopyyrim inematshini ye-novel, ifuthe lokulawula eliphezulu kunye nefuthe elide kwizinambuzane zeHomopteran, kwaye akukho mpembelelo kwizilwanyana ezizezilwanyana kunye nezinto eziluncedo. Inomdla kakhulu ngenxa yeempawu zayo zokhuseleko kwizityalo ezinje ngerayisi ngenxa yetyhefu ephantsi okanye ityhefu esezantsi. Ngokudibanisa izibulala-zinambuzane ezineendlela ezahlukeneyo okanye ezifanayo zesenzo, i-Insecticial Spectum iyakwazi ukwandiswa, ifuthe lokulawula elilinganayo linokuchithwa, kwaye umngcipheko wokumelana unokuncitshiswa.
IXESHA LOKUQALA: UPE-26 ukuya ku-2622